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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
TYPE 1 KOUNIS SYNDROME AND MULTIORGAN FAILURE SECONDARY TO METAMIZOLE
Author
Yusuf Savran*, Murat Emre Tokur, Bilgin Cömert, Dayimi Kaya
Email
yusufsavran@yahoo.com
keyword
Kounis syndrome, Anaphylaxis, Allergic angina, Metamizole, Multiple organ failure.
Abstract
Kounis syndrome is defined as acute coronary syndromes secondary to allergic insults.Various drugs, conditions and environmental exposure has been shown to cause Kounis syndrome. We report a 40 year-old male patient otherwise healthy who suffered of acute coronary syndrome and multiorgan failure after one tablet of metamizole consumption. Severe anaphylactic shock and multiorgan failure was treated by high dose vasopressor support, mechanical ventilation and plasmapheresis. He was discharged as healthy at the end of three weeks intensive therapy. This case highlights the occurence of acute coronary syndrome and multiorgan failure following drug induced anaphylaxis. Kounis syndrome should be kept in mind in case of an acute cardiac complication.
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