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Singapore Journal of Pharmaceutical Research

Volume 2, Issue 1, 2015
Mcmed International
Singapore Journal of Pharmaceutical Research
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorsjpr@mcmed.us
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Abstract
Title
SYNTHESIS & IDENTIFICATION OF BIS-(AZ-COMPOUNDS) VIA ALKYLATION OF DIMETHYL MALONATE
Author
*Rajaa Abed and Alameer Gafel
Email
rajaabed1998@yahoo.co.in
keyword
Di az, Di cycle, Di alkyl malonate.
Abstract
In this paper, dimethyl malonate has been used to the reaction with P -formal benzaldehyde forming the corresponding bis(Dimethyl malonate ) which ciclyze with di amine compounds to produce bis {(5, 6, 7) –membered of di aze cycles}, & some of them reacts with different amino compounds to produce corresponding bis substituted. The structures of the synthesized compounds have been confirmed by (FT.IR - spectra, H.NMR -spectra, C.H.N - analysis) & melting points.
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