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Scandinavian Journal of Pharmaceutical Science and Research

Volume 1, Issue 1, 2014
Mcmed International
Scandinavian Journal of Pharmaceutical Science and Research
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorsjpsr@mcmed.us
Journal Home page
http://mcmed.us/journal/sjpsr
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Abstract
Title
PHARMACOKINETICS IN GERIATRIC PATIENTS
Author
Subhashis Debnath*, Hima Bindhu P, Niranjan Babu M, Isaquiddhin Kureshi MD, Vanitha G
Email
shcppub@yahoo.com
keyword
Geriatric, Pharmacokinetics, Toxicity, Elderly.
Abstract
The complex process of aging is characterized by progressive loss in the functional capacities of organs, a reduction in mechanisms of homeostasis, and altered response to receptor stimulation. Medication therapy is among the most widely used and highly valued interventions for acute and chronic diseases of older adults, yet the use of drug therapy in the geriatric patient is one of the most difficult aspects of patient care. Alteration of the pharmacokinetics of these drugs in the elderly may necessitate adjustment of drug dosages to prevent toxicity or inadequate therapy. Recognition of the relationship between physiologic changes and drug pharmacokinetics is important to better prescribe the correct dose in the elderly population.
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