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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
THE RELATION BETWEEN ACUTE PHASE REACTANTS AND TRAUMA SEVERITY
Author
Rasim Yorulmaz1, Mehmet Kosargelir2, Arzu Denizbaşı3, Ozge Onur3, Tuba Cimilli Ozturk1, Hasan Demir1, Seçkin Ozgur Tekeli4
Email
ozberkozge@gmail.com
keyword
Trauma, ISS, GCS, Fibrinogen, CRP, Albumin, Ferritin, Mean arterial pressure.
Abstract
Trauma is a leading cause of death in adolescents. The ISS (Injury Severity Score) is an anatomical scoring system that provides an overall score for patients with multiple injuries. No biomarkers have been reported to have demonstrable clinical utility capable of indicating injury severity. This study was designed to compare the relationship of inflammatory reactants with trauma severity score (ISS) , Glascow Coma Score and search correlation. The ISS and GCS (Glascow Coma Scale) of trauma patients were calculated on admission to the ED, and acute phase reactant(CRP, Fibrinogen, Albumin, Ferritin) levels were evaluated. The main outcome measures were admission to hospital; need operation and ISS correlation with inflammatory markers. For statistical analysis, NCSS (Number Cruncher Statistical System) 2007 & PASS (Power Analysis and Sample Size) 2008 Statistical Software(Utah, USA) programs were used. Study enrollment included 59 patients who met the inclusion criteria. Based on Pearson’s correlation analysis, there were negative correlations between mean arterial pressure (MAP) and ISS as well as between fibrinogen levels and ISS. There was no correlation with other acute phase reactants like CRP, ferritin and albumin and ISS. There was a negative correlation between ISS and MAP. Low fibrinogen levels indicate more severe injury, and high ISS. Levels of other inflammatory markers don't correlate with severity of trauma
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