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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
EFFICACY OF TOPICAL ACYCLOVIR IN TREATMENT OF HERPETIC KERATITIS
Author
Koppolu Sreedhar Reddy 1* and Venkata Prasanna DP 2
Email
reddy.sreedhar.koppolu@gmail.com
keyword
Herpetic keratitis, Topical Acyclovir, Efficacy.
Abstract
Herpetic keratitis is a major cause of corneal blindness in the world. Several commercially available topical and oral antiviral drugs are currently available, oral antiviral drugs alone are not always effective in Herpetic keratitis. Thus, there had been a need for safe and effective topical antiviral agents against Herpetic keratitis. This study aimed to evaluate the efficacy of topical ophthalmic acyclovir applied five times daily as a treatment for herpes keratitis. 48 patients of Herpes simplex ocular disease who attended the outpatient department were included in study. Topical Acyclovir was found to be effective antiviral agent for the treatment of Herpetic keratitis showing an efficacy of 73 % of cases. In this study topical Acyclovir therapy was not effective in the treatment of stromal disease. Topical therapy is a potentially effective modality in herpetic keratitis
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