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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
ANTIOXIDANT ACTIVITY AND ANTIMICROBIAL STUDIES ON GARCINIA MANGOSTANA
Author
S. Nivetha*1 and D. Vetha Roy2
Email
snivetha_nivetha@yahoo.co.in
keyword
Garcinia Mangostana, Ethanolic extract, Antioxidant, Antimicrobial.
Abstract
The discovery of active biocompounds is a matter of urgency as most of the pathogens are getting resistance against number of drugs. Ethanolic extract of Garcinia mangostana peel analysed for its antioxidant and antimicrobial properties reveals higher amount of polyphenols (3.717 μg/ml) and flavonoids (2.98 μg/ml) compared to the selected fruit juices. Moreover against all the selected microbial strains Candida albicans, Candida tropicalis, Candida cruzi, Candida parapsolis, E.coli, Klebsiella pneumonia, Pseudomonas aeruginosa and Proteus mirabilis, significant activity is observed at both the concentrations 5000μg/ml and 10000μg/ml. Even against the multi-drug resistant E.Coli (18mm) and Candida albicans (13mm) remarkable inhibitory activity is recorded. Against E.Coli (18mm), Candida tropicalis (15mm) and Candida parapsolis (17mm) comparable activity is obtained with that of the control at the lower concentration itself.
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