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Acta Biomedica Scientia

Volume 1, Issue 2, 2013
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
ANTI-HYPERGLYCEMIC ACTIVITY OF ABUTILON INDICUM USING ALLOXAN INDUCED HYPERGLYCAEMIA IN MICE
Author
Panasa Harish Kumar*, Konda Mounika, P. Madhu Kiran, E. Kavya, S. Girisha
Email
panasaharishkumardph@gmail.com
keyword
Abutilon indicum, Anti-hyperglycaemic activity, Alloxan.
Abstract
During past several years, there has been growing interest among the usage of various medicinal plants from traditional system of ailments. The objective of this study was to evaluate the anti-hyperglycemic effect from alcoholic extract derived from the Abutilon indicum plant. Oral administration of the extract (200mg/kg body weight) led to a significant reduction in plasma glucose levels in diabetic mice (by inducing alloxan) as compared with untreated mice, and this was at a faster rate than the use of antidiabetic drug Glibenclamide. Phytochemical screening also revealed that the extract contains alkaloids, flavonoids, tannins, glycosides that could account for the observed pharmacological effect
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