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Singapore Journal of Pharmaceutical Research

Volume 2, Issue 1, 2015
Mcmed International
Singapore Journal of Pharmaceutical Research
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorsjpr@mcmed.us
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Abstract
Title
ANTI-HYPERLIPIDEMIC ACTIVITY OF THE METHANOLIC EXTRACT OF EUGENIA JAMBOLANA BARK IN HIGH FAT DIET INDUCED HYPERLIPIDEMIC RAT
Author
Shankar M*1, Gowri Shankar NL2, Laxman G2, Vidhyavanthi B2, Ramya Priya T2, Gopalakrishna E2, Swathi B2
Email
shankarmanichellappa@gmail.com
keyword
Antihyperlipidaemic, Eugenia jambolana, Lipoproteins, Atorvastatin.
Abstract
Eugenia jambolana is therapeutically evaluated for anti-hyperlipidemic activity. Significant anti-hyperlipidemic effects were obtained as evident from the restoration of biochemical parameters altered by cholesterol towards the normal. Almost normal histological appearance of liver was observed in treated groups. Among the three doses, 400 mg/kg showed better activity. However, the activity was found to be less than the standard atorvastatin given at 1.2 mg/kg dose. The results showed that the methanolic extract of Eugenia jambolana has potential hypolipidemic effect along with recovery of liver functions.
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