Australian Journal of Pharmaceutical Research

A STUDY OF ANTIBIOTIC SUSCEPTIBILITY PATTERN OF BACTERIOLOGICAL ISOLATES ON PEDIATRIC PATIENTS WITH INFECTIOUS DISEASES

1Dayana Nicholas*, 1Kenneth Nelson, 1Muralidharan Selvadurai and 2Samson P. George

dayanicholas@gmail.com

Antibiotics, Staphylococcus aureus, Streptococcus pneumonia, Escherchia coli, Klebsiella pneumonia and Meningo coccus.

Antibiotics are one of the most often prescribed drugs for children's infectious diseases. This study is aimed to determine and analyze the antibiotic susceptibility pattern of bacterial isolates using microdilution method and to identify the effective antibiotics prescribed by antibiotic sensitivity pattern on pediatric patients from a private hospital for one year period. We reviewed the 612 case records from the pediatric ward, who fulfilled the inclusion criteria were studied. Antibiotic susceptibility pattern were performed and each case records, blood culture reports were recorded. Among the (n=612) blood culture reports, the total positive blood culture reports monitored was 33% (n=202) with the bacteriological organisms Staphylococcus aureus, Streptococcus pneumonia, Escherchia coli, Klebsiella pneumonia and Meningo coccus. The most frequent bacterial organisms isolated were Staphylococcus aureus, Streptococcus pneumonia, Escherchia coli, Klebsiella pneumonia and Meningo coccus respectively. S. pneumoniae was found to be most sensitive towards amoxicillin, followed by cloxacillin, chloramphenicol, ciprofloxacin, ampicillin, and least sensitive towards gentamycin, and penicillin. M. coccus was shown to be highly sensitive towards penicillin, ciprofloxacin, and least sensitivity towards ampicillin, cloxacillin, amoxicillin, gentamycin, and chloramphenicol. Staphylococcus aureus was sensitive against chloramphenicol and Klebsiella pneumoniae was found to be sensitive against chloramphenicol. S. pneumoniea and E. coli were sensitive to amoxicillin. Micrococcus was found to be sensitive with penicillin, ciprofloxacin followed by ampicillin. The study is concluded with most of antibiotics were not sensitive against all bacteria. Hence the antibiotics can be considered and prescribed to the infected pediatrics only after the antibiotic sensitivity pattern tests.