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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
DENGUE INDUCED SIADH (SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION)
Author
Kavita Krishna1, Gadkari N3, Aniket Oswal2*, Aditya Bhabhe4, Vaibhav Lotke3, Jay Patel2
Email
cammello2011@gmail.com
keyword
Dengue virus, Hyponatremia, hypovolaemia, SIADH.
Abstract
Dengue virus has long been considered as a non-neurotropic virus, as animal studies have shown that virus does not cross blood brain barrier. However, many cases of Dengue encephalopathy have been reported. Hyponatremia may be found in association with dengue fever and is thought to be caused by peripheral fluid extravasation and resulting intravascular hypovolaemia. But hyponatremia due to syndrome of inappropriate secretion of anti-diuretic hormone (SIADH) in Dengue fever is rare. We report a male aged 45 years who presented with altered sensorium since one day, diagnosed as Dengue fever (Dengue Ns1Ag positive) with thrombocytopenia and hyponatremia. He was admitted and further investigations revealed SIADH. He responded well to cautious sodium replacement, recovered completely and was discharged after one week.
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