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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
LIPIDS AND RHEOLOGIC INDICES AMONG BLOOD DONORS IN ILE-IFE METROPOLY NIGERIA
Author
Adegunloye Aramide B1, Oke Olusegun Taiwo*2, Emelike Okechukwu Felix3, Oyedeji Samuel Oyewole2, Obazee Yetunde Docas4
Email
oketaiwo@yahoo.com
keyword
Haemorheology, Plasma viscosity, Whole blood viscosity, Fibrinogen Concentration, Haematocrit.
Abstract
In this study a total of eight (8) male none remunerated donors were recruited. A validated questionnaire was administered to collect data pertaining to their life styles. None of them was found to be cigarette smoker nor drink alcohol and the standard criteria for blood donor fitness were met by all of them and instruction to have their last meal two hours before donation were also adhere strictly. A pre and post donation samples were collected 1, 24, 48, 72 and 120 hours were collected. Among the parameters analysed were;- Packed cell volume (PCV), Relative plasma viscosity (RPV), Relative whole blood viscosity (RWBV), Plasma fibrinogen concentration (PFC), Cholesterol (CHOL), Triglyceride (TG), Sodium (Na+) and Potassium (K+). The experimental differences seen in pre and 1hr post samples were not statistically significant (p>0.05). When the result of 24hrs post donation samples were compared to pre samples, there were no significant difference (p>0.05). Statistically significant differences were seen in RWBV and Na+ only when 48 and 72 hrs post samples were compared to pre-samples (p<0.05). In the 120hs post samples significant difference was seen only in sodium (p<0.05), relative stable haematocrit was observed throughout the period of this study. In conclusion bloodletting is capable of inducing quick and significant hypolipidemic effect which could predetermine improved haemorheology and overall microcirculatory efficiency. This procedure could be therapeutic for dyslipidemic and hyperviscosity patients and myocardial protection and prevention.
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