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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
MANAGEMENT OF A TRANSFUSION RELATED ACUTE LUNG INJURY (TRALI) IN SPLENECTOMY
Author
Iramnaaz Shaikh1* and Bhaarat Maheshwari2
Email
ashi_naaz33@yahoo.com
keyword
TRALI, pulmonary edema, blood transfusion
Abstract
TRALI is a life threatening adverse effect of transfusion. It is characterized by dyspnoea , cough and pulmonary edema within 6 hrs of transfusion. Most commonly it is caused by donor HLA antibodies that reacts with recipient antigens . It may also be caused by biologically active compounds accumulated during storage of blood products which are capable of priming neutrophils . Without a gold standard, the diagnosis of TRALI relies on high index of suspicion and on excluding other types of transfusion reactions . We report a case of TRALI in a patient who was posted for splenectomy and required blood transfusion . Patient developed acute pulmonary edema within 1 hour of commencing transfusion . This was managed with post op ventilatory support , Oxygen , Diuretics and Steroid . Patient improved rapidly and later got discharged without any complication.
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