TELL : +91 0 99 08 87 07 06

 Mcmed International ®: Largest Journal Publication in world

International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
Recommend to
A Friend  | A librarian
Purchase
Purchase Issue
Abstract
Title
THROMBOSIS: PRESENTATION OF A FACTOR XII DEFICIENCY IN 10 MONTHS OLD CHILD - A RARE CASE
Author
Prosenjit Ganguli*, Rigvardhan, Jyoti Kotwal
Email
prosenjitganguli@gmail.com
keyword
Thromboplastin, Venous thrombosis, Prothrombin time.
Abstract
Since its first discovery in 1955, coagulation factor XII deficiency was, quite surprisingly, linked with thrombosis instead of hemorrhage; indeed, John Hageman ultimately died from pulmonary embolism. After this, several reports have highlighted the association between both arterial and venous thrombosis and factor XII deficiency; however, a causal relationship is still questioned. Here, we report the case of a 10 month old male child with factor Hageman deficiency who presented with painful swelling of right lower calf. Detailed clinical examination and color Doppler confirmed venous thrombosis of right calf. There were no known predisposing factors for venous thrombosis in such a young child. Coagulation work up revealed normal prothrombin time (PT) but prolonged activiated partial thromboplastin time (APTT). Keeping this in mind factor assays were performed which confirmed factor XII deficiency
Download Broucher
Back to Top >>>>