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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
THROMBOTIC THROMBOCYTOPENIC PURPURA ASSOCIATED WITH RAPIDLY PROGRESSIVE LUPUS NEPHRITIS IN PREGNANCY – EFFICACY OF CYCLOPHOSPHAMIDE AND STEROID PULSE ALONE WITHOUT PLASMAPHERESIS: A CASE REPORT
Author
Anvar M I1, Raghavendra Nagammanavar2, Bellara Raghavendra3*
Email
bellararaghu@gmail.com
keyword
Gitelman Syndrome, Hypokalemia, Hypomagnesemia
Abstract
There are few reported cases in the literature of Thrombotic microangiopathy (TTP) associated with Systemic Lupus Erythematosus (SLE). We describe a case of Thrombotic Thrombocytopenic Purpura (TTP) which presented along with rapidly progressive lupus nephritis with edema, proteinuria, hypertension, thrombocytopenia, microangiopathic hemolytic anemia and progressive rise in serum creatinine from 1.4 mg/dl to 4.2 mg/dl over a period of 10 days in pregnant woman who was having 20 weeks of amenorrhoea who was successfully treated with pulse cyclophosphamide and pulse methylprednisolone, with patient normalizing her renal function. Further experiences are needed whether intensive and prompt treatment with pulse cyclophosphamide and corticosteroids will lead to favorable outcome in cases of TTP associated with SLE.
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