TELL : +91 0 99 08 87 07 06

 Mcmed International ®: Largest Journal Publication in world

International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
Recommend to
A Friend  | A librarian
Purchase
Purchase Issue
Abstract
Title
CHILDHOOD CNS VASCULITIS A NOVEL CHALLENGE IN PEDIATRIC RHEUMATOLOGY CLINIC, A CASE SERIES STUDY
Author
Farhad Salehzadeh1* and Omid Akbari2
Email
salehzadeh_f@yahoo.com
keyword
Vasculitis, CNS vasculitis, Brain MRA.
Abstract
Primary CNS vasculitis of childhood (cPACNS) is an inflammatory vascular process of CNS. It is considered a very novel and challenging clinical problem in pediatric rheumatology and neurology clinic. From 1994 to 2014 at pediatric rheumatology clinic, patients <18 years of age were included to this study as having cPACNS if they had: a clinical diagnosis of primary CNS vasculitis, and MRA findings demonstrating arterial stenosis and or aneurism not attributable to other causes. 22 patients were enrolled this study with mean age 10 years, 12 patients (54%) were female. The mean delayed time to diagnosis was 4 years. The most common neurologic symptoms were headache (88%) then seizure and mental disorder in (45%). Fever was in (54%) and positive ANA result in (31%) patients. 14 patients (63 %) showed abnormality in both MCA and ACA, whereas PCA showed this abnormity in 36% (8) patients. Most of patients 86 %( 19) had normal EEG findings. Five patients (22%) had severe and permanent neurological sequel. It seems cPACNS is unfamiliar disorder and we recommend that in any patient with unexplained headache, seizure and mental disorder CNS vasculitis should be considered.
Download Broucher
Back to Top >>>>