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International Journal of Advanced Oncology Research

Volume 6, Issue 1, 2019
Mcmed International
International Journal of Advanced Oncology Research
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorijaor@mcmed.us
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Abstract
Title
PHOTODYNAMIC THERAPY-A NEW EMERGING TREND IN DENTISTRY
Author
Kamal Sagar1*, Arundeep Kaur2, Vijay Kumar3, Parveen Ranga4, Farrukh Farraz5, Shruti Tandon6
Email
dr.kamalsagar@gmail.com
keyword
Photodynamic Therapy, Photosensitizers, Novel Treatment, Oral Premalignant and Malignant Lesions.
Abstract
Photodynamic therapy is a novel, non-invasive therapeutic approach with increased pathogen and site specificity. It is a powerful laser-initiated photochemical reaction, involving the use of photosensitizer (dye) that is activated by light of specific wavelength to form toxic oxygen species like singlet oxygen and free-radicals. These chemical species are very reactive, can damage proteins, lipids, nucleic acids and other cellular components. Various applications of photodynamic therapy are treatment and diagnosis of cancer, in bacterial, fungal, parasitic and viral infections, periimplantitis, periodontitis, endodontic infections and oral biofilms such as plaque. The biggest advantage of PDT is the absence of any genotoxicity, no mutagenic effect and no risk of developing resistance to its antimicrobial action and increased healing process which favours its long-term use and safety. Thus, PDT represents a novel therapeutic approach in the management of various medical as well as dental conditions.
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