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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
INTRACRANIAL ANAPLASTIC HEMANGIOPERICYTOMA: A DIAGNOSTIC DILEMMA
Author
Binny Khandakar*, Prasenjit Sen Ray, Soumit Dey, Moumita Maiti, Neepamanjari Barman, Palas Bhattacharyya, Ranu Sarkar
Email
binikhandakar@gmail.com
keyword
Anaplastic; Hemangiopericytoma; Radiotherapy; Intracranial; Dura-Based.
Abstract
Intracranial hemangiopericytoma (HPC) is an extremely uncommon and aggressive tumor with high rate of local recurrence and distant metastasis. These tumors represent <1% of all central nervous system neoplasms. The anaplastic variant is described as WHO grade III lesion. Here we describe a case of intracranial anaplastic hemangiopericytoma diagnosed at our institute. A fifty years old male patient presented with progressive headache and repeated bouts of vomiting for last three months. Imaging studies revealed a large dura based mass with evidence of cortical compression. Based on radiology, a provisional clinical diagnosis of meningioma was made and the patient subsequently underwent open craniotomy for excision of the tumour. Based on morphology with supplementary immunohistochemistry, a final diagnosis of anaplastic hemangiopericytoma was offered. Microscopically, these rare tumors are highly cellular, composed of oval to spindle cells, with rich vascular network and pericytomatous pattern. Hemangiopericytoma is more aggressive and has a relatively poorer prognosis than the commoner dural based tumor, meningioma. Post-operative radiotherapy may be considered to reduce recurrence and improve survival. A correct diagnosis is essential for a proper management of these cases.
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