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American Journal of Oral Medicine and Radiology

Volume 5, Issue 2, 2018
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
Journal Home page
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Abstract
Title
AUTOFLUORESCENCE SPECTROSCOPY OF SMOKERS - AN IN VIVO STUDY
Author
M Rajmohan1, R Murali Naidu2*, R Amsaveni3, D Thamaraiselvi3, Deepasree M3
Email
mroralpathologist@gmail.com
keyword
Autofluorescence, Smokers, Spectroscopy, Excitation, Emission.
Abstract
Use of smoking tobacco is a major public health challenge in India. It requires a reliable technique that will useful for mass screening of the public and to detect the early changes before it clinically manifest. Aims to identify the differences in autofluorescence spectra of normal oral mucosa and smoker’s oral mucosa. Group I consists of 20 individuals with normal mucosa and Group II consists of 40 individuals with smoking habit. Only males were included in this study and their age ranging from 25 to 35 years. In vivo fluorescence spectra from both groups were obtained by using hand held fiber optic probe attached to Varian Cary Eclipse fluorescence spectrophotometer. Independent-Samples T test was used for statistical analysis. P value was obtained to discriminate the statistical differences between the two groups. The averaged excitation and emission spectra of normal and smoker’s mucosa showed significant differences statistically. Autofluorescence spectroscopy can be used effectively to differentiate the smoker’s oral mucosa from normal oral mucosa.
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