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European journal of molecular biology and biochemistry

Volume 1, Issue 5, 2014
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
ANTIMICROBIAL AND CYTOTOXIC ACTIVITIES OF MARINE STREPTOMYCES SP. PA-32
Author
P.Kiruthika and S.Bhuminathan
Email
master.maniji@gmail.com
keyword
Marine actinomycetes, Antimicrobial, Antifungal.
Abstract
Marine actinomycetes are potential provider of novel bioactive metabolites and currently emerged as an important source for natural products with unique chemical diversity. The main aim of the study was to evaluate the antimicrobial and cytotoxic potential of crude extract of Marine Streptomyces species isolated from mangrove sediment, Nagapattinum, Tamilnadu, India. Primary and Secondary screening for antimicrobial activity was determined by Cross streak method and Agar disc diffusion method respectively. Among the strains, Streptomyces sp. PA32 extract shows anti bacterial, anti fungal and Cytotoxic activities. The results of this study indicate that Marine actinomycetes Streptomyces sp. PA32 can able to produce new drug molecule against pathogenic microorganisms.
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