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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
INCIDENCE OF BACTERIAL UROPATHOGENS AMONG DIABETIC PATIENTS
Author
P. Karthik, P. Sivagurunathan*, C.Uma and M. Bhuvaneswari
Email
sivaguru1981@yahoo.com
keyword
Antibiotic; Diabetic; Surveillance; UTI; Uropathogen.
Abstract
Urinary Tract Infections (UTIs) occur more frequently in diabetic than in non-diabetic patients and have been proven to be the primary cause of renal failure. This study was to investigate the prevalence of UTIs in clinically diagnosed patients with diabetes and to determine the Uropathogens responsible for UTIs as well as the antimicrobial susceptibility pattern. A total of 50 diabetic patients, i.e. 25 female and 25 male, with symptomatic UTI were included in this study. All urine samples were processed in the lab following standard laboratory protocol. Among the study cases, 48% male and 72% female diabetic patients had positive growth from urine. The commonest Uropathogen obtained was Escherichia coli (48%) followed by the Klebsiella pneumonia (28%), Pseudomonas (16%), Staphylococcus aureus (16%) and Proteus (12%) respectively. The antibiotic susceptibility for the five predominant species of bacteria revealed high resistance to Penicillin, Erythromycin, Ampicillin and susceptibility to Ciprofloxacin. The prevalence rate of UTI was high in diabetic female than male patients. Gram negative pathogens especially E. coli was predominate among the causative agents of UTIs. Ciprofloxacin found to be containing broad spectrum activity against both gram positive and gram negative pathogens.
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