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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
CHROMATOGRAPHIC STUDY OF THE MULTICOMPONENT ANTIFUNGAL CREAM
Author
I.Vlasenko, Аram Dulah, L.Davtyan, G.Petyunin
Email
vlasenko_iryna@mail.ru
keyword
Quantitative Content, Chromatographic Parameters, The active pharmaceutical ingredient, Delay time, Peaks.
Abstract
In the past decade there has seen a trend towards manufacturing of multi-component medicinal products, which is associated with a modern approach to the combined pharmacotherapy – using multiple active pharmaceutical ingredients (APIs) in one dosage form. Enhancement of the pharmacological effect is achieved by the synergism or combined interactions of ingredients [1]. However, the combined dosage forms tend to be involved in various inter-component physicochemical interactions, which may affect the stability of the product during its manufacture, storage and, ultimately, its therapeutic efficacy. Therefore, the development of standardization methods for multi-component medicinal products is a relevant objective of pharmaceutical science [2-5].
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