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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
A STUDY OF BONE MARROW DENSITY (BMD) AND BONE MINERAL CONTENT (BMC) AS A MEASURE OF OSTEOPOROSIS AND RELATED COMPLICATIONS IN THALASSEMIA MAJOR PATIENTS
Author
1Ujjwal Bandyopadhyay, 2Sarmila Guha (Banerjee), 3Arijit Sinha, 4Aparajita Samaddar, 5Subhrajyoti Mitra, 6Pradyut kumar Pan
Email
ujjwal.kalindi@gmail.com
keyword
Thalassemia, osteoporosis, bone marrow density (BMD), bone mineral content (BMC).
Abstract
Conservative management with blood transfusion and treatment of complication is the cornerstone of management of Thalassemia major patients. With this measure there is remarkable improvement in life expectancy of Thalassemia patients. But as these patients age, osteoporosis is emerging as a major complication and an important cause of morbidity. So the present study was set up to study the important parameters identifying osteoporosis in thalassemia patients. 54 Thalassemia (thal) major patients and 54 age and sex matched control were studied to see the bone mineral density (BMD) and bone mineral content (BMC) of lumber spine and femoral neck and to compare the same with values of normal control. (L4-L5) spine BMD values of thal major patients are lower than that of age and sex matched control group in our study. Bone mineral content (BMC) at the level of L4-L5 is significantly lowered in thal major patient with respect to control group and the lowering is statistically significant. Average BMC value of femoral neck of thal major patients is also lower than that of normal control. Results pointed out the fact that study of BMD and BMC in these patients are very good index of osteoporotic status of these patients and annual measurement of these parameters can be done to monitor the complication and morbidity related to osteoporosis.
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