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European Journal of Pharmacology & Toxicology

Volume 1, Issue 1, 2014
Mcmed International
European Journal of Pharmacology & Toxicology
Issn
XXX-XXXX (Print), XXXX-XXXX (Online)
Frequency
bi-annual
Email
editorejpt@mcmed.us
Journal Home page
http://mcmed.us/journal/ejpt
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Abstract
Title
EFFECT OF CHRONIC CIGARETTES SMOKING ON SERUM TESTOSTERONE, LUTINIZING HORMONE AND PROLACTIN LEVELS AMONG SUDANESE SMOKERS
Author
Ahmed Khalifa Aboelgasim* and AbdElkarim A Abdrabo
Email
abdrabokarim@hotmail.com
keyword
Abstract
Cigarette smoking is highly prevalent among men. Many studies have evaluated the effect of cigarette smoking on levels of male reproductive hormones; however, the findings still remain controversial. The main objective was to study the effect of cigarette smoking on Luteinizing, Prolactin and Testosterone hormones in male. Hundred blood samples were collected from apparently healthy Sudanese individuals, smoker (N= 50) and non smoker as control (N=50). All volunteers were recruited from Omdurman area- Khartoum- Sudan. The samples measured using ELISA full automated hormone analyzer (Human-Ouno, Germany). This study showed that Luteinizing hormone levels among smokers and nonsmoker were (mean ± SD 3.16±1.09 ng/ml, and 3.17±1.23 ng/ml), respectively with no significant difference between meansP =>0.05), also it showed no significant differences in prolactin levels in smokers (M±SD = 7.3±2.0ng/ml) compared with control group (M±SD = 7.6±1.8ng/ml, P = 0.83). While there is significant lower levels in testosterone [M±SD =3.0±1.9ng/ml] compared with control group (M±SD = 6.1±2.8ng/ml), P = 0.03. The study concluded that there was significant low level of testosterone in smokers compared to nonsmokers, while there were no significant differences on serum levels of Luteinizing Hormone and prolactin. Key word: Luteinizing hormone- Prolactin- Testosterone – Smoking- Smoking.
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