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Acta Biomedica Scientia

Volume 1, Issue 2, 2013
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
RECENT ADVANCES IN INTRANASAL DRUG DELIVERY SYSTEMS
Author
Chinmaya Keshari Sahoo*1, Dibyalochan Mohanty2, R.Soundharya3, Kole Bhavana3, G.Akshay Kumar3
Email
sahoo.chinmaya83@gmail.com
keyword
Intranasal drug delivery,Nasal route, Gastric degradation, Hepatic first pass metabolism, vaccines.
Abstract
Intranasal drug delivery provides as a non-invasive route for drugs. The nasal mucosa offers numerous benefits as a target tissue for drug delivery, a wide variety of therapeutic compounds may be administered intra nasally for topical, systemic and central nervous system. Nasal route is more suitable for those drugs which cannot be administered orally due to gastric degradation or hepatic first pass metabolism of the drug. Intranasal drug delivery is found much promising route for administration of peptides and protein drugs, vaccines. This present review has focused on mechanism, factors affecting nasal drug absorption, applications etc.
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