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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
FLOATING DOSAGE FORM IS A MEDICAL BOON IN THE DRUG DELIVERY SYSTEM
Author
1D.K. Sanghi and *Rakesh Tiwle
Email
rakesh_tiwle@rediffmail.com
keyword
Gastro retentive systems, Buoyancy, Gastric retention time, Floating tablet, Floating capsule, Floating microsphere.
Abstract
Floating drug delivery system is a medical boon in the oral delivery system, because the drugs having narrow absorption window in the gastrointestinal tract or have poor absorption. There are several techniques like mucoadhesive systems, high density systems, floating drug delivery system, low density systems, superporous hydrogels and magnetic systems, have been formulated. Floating drug delivery systems (FDDS) or hydro dynamically controlled systems are low-density systems that have sufficient buoyancy to float over the gastric contents and remain buoyant in the stomach without affecting the gastric emptying rate for a prolonged period of time. While the system is floating on the gastric contents, the drug is released slowly at the desired rate from the system is achive. In this system various dosage forms available like capsules, tablets, granules and microspheres etc by reviewing this article floating dosage forms is the current & recent developments / trends in the drug delivery system.
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