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European journal of molecular biology and biochemistry

Volume 1, Issue 5, 2014
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
A STUDY ON THE ROLE OF PROTEIN – UREA RATIO IN SERUM AS AN ASSIMILATION INDEX IN THE MANAGEMENT OF PROTEIN DEFICIENCY
Author
Jusmita Dutta1* and Sunil Aswani1
Email
dutta.jbio@rediffmail.com
keyword
Serum Total Protein, Serum Albumin, Serum Urea.
Abstract
Protein deficiency is a major health problem in the world today. It may be defined as the state, which results due to a relative or absolute lack of protein in the diet. Aims to study the serum protein: urea ratio as an indicator of the extent of effectiveness of protein supplementation in protein deficiency. Settings and Design: longitudinal study done in Gauhati Medical College and Hospital. Sixty individuals, (30 cases and 30 controls) was given Protein supplementation at the rate of 1gm/kg body weight from day 1 and then their serum total protein, serum albumin, serum urea, serum fasting glucose, serum creatinine, serum total protein to urea ratio, and serum albumin: urea ratio. Statistical analysis used: unpaired t test and one way Anova test. Significant difference was seen on day 0,8 and 15 between cases and control in the serum total protein, serum albumin, serum urea, serum creatinine and serum total protein to urea ratio. In cases a significant difference was seen in all parameters on days 0, 8 and 15 except serum fasting glucose. Serum protein: urea ratio can be used as an assimilation index which would help in locating the metabolic stage of the patient; however we recommend the further multicentric study with large sample size.
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