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International Journal of Advances In Case Reports

Volume 11, Issue 1, 2024
Mcmed International
International Journal of Advances In Case Reports
Issn
XXX-XXXX (Print), 2349 - 8005 (Online)
Frequency
bi-annual
Email
editorijacr@mcmed.us
Journal Home page
http://mcmed.us/about/ijacr
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Abstract
Title
RANDOMISED COMPARATIVE STUDY OF ACECLOFENAC THIOCOLCHISIDE FIXED DOSE COMBINATION AGAINST ACECLOFENAC ALONE IN TREATMENT OF ACUTE NUCHAL PAIN: SAFETY AND EFFICACY ASSESSMENT
Author
Sheikh Irfan Bashir* and Shuja Rashid
Email
sheikhirfanb@gmail.com
keyword
Acute Nuchal Pain, Randomised Trial of Aceclofenac against Aceclofenac Thiocolchiside combination, Treatment Acute Nuchal Pain, Neck Pain and NSAIDS, Neck Pain and Thiocolchiside.
Abstract
Nuchal pain is one of the most common reasons for consulting health care personnel. There are multiple modules to treat it, but all of them lack evidence. There have been no randomised trials for efficacy assessment of various drugs used in the treatment of nuchal pain. This study was conducted to assess efficacy and safety of Thiocolchiside Aceclofenac combination against Aceclofenac alone. Out of 145 patients randomised into two groups 138 completed the study. Patients were assessed by Visual Analogue Scale, Shafat’s Range of Motion Index and Shafat’s Nuchal Tenderness Index both before the start of treatment and on Tenth day of treatment. There was significant improvement in all scores in both groups. The combination therapy group showed better response in all scales than the aceclofenac alone group. The Shafat’s Range of Motion Index and Shafat’s Nuchal Tenderness Index showed significant improvement as compared to the Aceclofencac alone group with P<0.01. VAS showed better results in combination therapy than aceclofenac but the results were not statistically significant. All patients were given proton pump inhibitor during the treatment regime as a prophylactic measure for prevalent acid peptic disorder in the population. Few patients among combination therapy group developed dizziness with none of them requiring additional treatment. The study favours the use of thiocolchiside aceclofenac combination in the treatment of acute nuchal pain.
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