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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
ORAL TOXICITY STUDY OF ETHANOLIC EXTRACT OF FICUS CARICA IN FEMALE SWISS ALBINO MICE
Author
*P.Amudha and 1S.Venkataraman
Email
amudha.cology@gmail.com
keyword
Oral toxicity, Biochemical Parameters, Haematological Parameters, Ficus carica Linn.
Abstract
The plant Ficus carica Linn is traditionally used for in different disorders such as gastrointestinal, respiratory, metabolic and cardiovascular disorders. The present investigation was carried out to evaluate the safety of aqueous extract of Ficus carica (L.) (AEFC) and ethanol extract of Ficus carica (L.) (EEFC) by determining its potential toxicity after 28 days repeated administration in albino mice. During the study, body weight, general behaviors, morbidity and mortality were observed. On 28th day, Biochemical parameters and haematological parameters were estimated and also brain, heart, liver and kidney were processed for histopathology studies. EEFC and AEFC 200 and 400mg/kg/p.o treated groups did not show significant changes in body weight, general behaviors, biochemical parameters and haematological parameters when compared to control. Histopathological studies suggest that no pathological changes in EEFC and AEFC treated animals.
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