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European journal of molecular biology and biochemistry

Volume 1, Issue 5, 2014
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
POSTPRANDIAL LIPEMIA AND POSTPRANDIAL ENDOTOXEMIA IN NORMAL PREGNANCY AFTER 20 WEEKS OF GESTATION (NP) AND PRE-ECLAMPSIA (PE)
Author
Gaffar Sarwar Zaman
Email
drgszaman@gmail.com
keyword
Endotoxin, Pre-eclampsia, Normal pregnancy, Total cholesterol, LDL-Cholesterol, Triglycerides.
Abstract
To analyze postprandial lipemia and postprandial endotoxemia in normal pregnancy and pre-eclampsia. Materials and Methods: Fasting and postprandial total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides were determined sequentially in blood samples. Serum LPS concentrations were measured by endotoxin assay, based on a Limulus amebocyte extract. The endotoxin levels were determined in serum of normal pregnancy and pre-eclampsia at fasting, 1 hr., 2hr, 3 hr. and 4 hr. and their levels related with postprandial lipemia in the same conditions. Fasting and postprandial total cholesterol, LDL-cholesterol and triglycerides were increased more in pre-eclampsia than in normal pregnancy. Similarly endotoxin levels were also increased significantly in fasting and postprandial pre-eclamsia. The potential of the endotoxin in the development of an early-stage specific diagnostic biomarker for Pre-eclampsia is also emphasized.
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