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Acta Biomedica Scientia

Volume 13, Issue 1, 2026
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
THE IMPACT OF HYPOTONIC CISPLATIN INTRAOPERATIVELY ON NON-SMALL CELL LUNG CANCERS WITH PROMISE PLEURAL LAVAGE CYTOLOGY
Author
Dr. Maddi Sai Venkatesh
Email
keyword
Intrapleural cisplatin, non-small cell lung cancer, Pleural lavage cytology, Carcinomatous pleuritis, Survival rates.
Abstract
The purpose of this study is to examine the effects of intraoperative intrapleural hypotonic cisplatin treatment on patients with non-small cell lung cancer (NSCLC) and positive results from pleural lavage cytology after surgery.This study offers information about survival rates and recurrence history despite the limited recruitment during phase III due to a low enrollment rate. A total of 58 patients were randomly selected for each group, and recurrence rates and 3-year survival were determined. There was a significant decline in re-occurrences of carcinomatous pleuritis in the treatment group (8 vs 42). In comparison with similar studies, the 3-year survival rates of the treatment and control groups were both high. The results suggest that intraoperative hypotonic cisplatin therapy might increase patient outcomes and prevent pleural recurrence. This treatment method will be validated by more prospective research and made more efficient through more research.
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