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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
PYRIDAZINONES: A WONDER NUCLEUS WITH SCAFFOLD OF PHARMACOLOGICAL ACTIVITIES
Author
Sonakshi Seth, Amit Sharma and Dev Raj*
Email
rajandev5655@gmail.com
keyword
Pyridazinones, Levosimendan, Amipizone, Indolidan, Imazodan and Pyridazinones, Levosimendan, Amipizone, Indolidan, Imazodan and Pyridazinones, Levosimendan, Amipizone, Indolidan, Imazodan and Levosimendan,Amipizone, Indolidan,Imazodan and Pimo
Abstract
During recent years pyridazinones have been a subject of intensive research owing to their wide spectrum of pharmacological activities. The pyridazinone derivatives show a wide spectrum of biological activities, as described in the literature.A number of compounds such as Levosimendan, Amipizone, Indolidan, Imazodan and Pimobedan are few examples of pyridazinones that are active as cardiotonic agents. The synthesis of novel pyridazinone derivatives and investigation of their chemical and biological activities have gained more importance in recent years. The biological profile of these new generations of pyridazinones presents much progress with regards to the old compounds.
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