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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
EFFECT OF PYRIDOXINE SUPPLEMENTATION ON URINARY CALCIUM AND OXALATE LEVELS IN HEALTHY INDIVIDUALS AND RENAL STONE PATIENTS: A COMPARATIVE STUDY
Author
Dr Lalitha Devi S
Email
keyword
Urolithiasis, urinary stones, calciuria, oxaluria, and pyridoxine supplementation.
Abstract
A study was conducted to examine the effects of pyridoxine (Vitamin-B6) supplementation on calciuria and oxaluria in 40 healthy subjects and 34 subjects with renal stones. Calcium and oxalate levels in the urine were determined in presupplementation periods and after each 20 day interval during supplementation in both healthy individuals and stone patients. Depending on their pre-supplementation (baseline) oxaluria levels, stone patients were divided into mild and moderate hyperoxaluriac groups. Patients with urinary stone formed decreased their mean 24-hour urinary oxalate levels significantly when supplemented with 10 mg pyridoxine for 60 days at a rate of 10 mg/day. Controls, however, showed only a mild decrease in oxaluria levels. In both controls and stone patients, pyridoxine supplementation resulted in only mild and not significant decreases in mean calciuria levels. In light of results, pyridoxine therapy was discussed in relation to oxalate urolithiasis
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