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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
Comparative Evaluation of Sonication and Maki Methods for Diagnosing Catheter-Related Bloodstream Infections in ICU Patients: A Prospective Observational Study
Author
Dr Anurag Chitranshi
Email
keyword
Sonication, Colonization, Bloodstream Infection
Abstract
To identify catheter-related bloodstream infections (CRBSI) in ICU patients, we compared sonication and Maki methods. Materials and methods: A prospective and observational study was conducted in one Intensive Care Unit. Study participants were patients with a central venous catheter (CVC) in place for at least seven days and at least one case of catheter-related infection (CRI) (new fever or sepsis episode). The catheter tip was sonicated using the Maki technique. AUCs of Maki, sonication, and methods together were evaluated to diagnose catheter tip colonisation and CRBSI. The 87 CRI suspect incidents collected 94 CVC. The number of catheter-tip colonizations was 14 and the number of cases of CRBSI was 10. Among the 14 catheter tip colonization cases, 7 (50.0%) were detected using both Maki and sonication techniques, 6 (42.9%) were revealed using Maki technique alone, and 1 (7.1%) was found using sonication alone. Out of the ten CRBSIs, six (60.0 percent) were identified using both Maki and sonication techniques, four (40.0 percent) using only Maki, and none using only sonication technique. AUCs of Maki technique versus sonication technique for diagnoses of CRBSI (p=0.02) and catheter tip colonization (p=0.03) are higher than those of sonication technique. No significant differences in AUC between Maki technique and combination procedures were observed in the diagnosis of catheter tip colonization (p=0.32) or CRBSI (p=0.32). Sonication was not shown to be an effective way to diagnose catheter tip colonization and CRBSI.
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