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American Journal of Oral Medicine and Radiology

Volume 5, Issue 2, 2018
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
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Abstract
Title
ASSESSMENT OF ANTRAL FOLLICLE COUNT AND ANTIMULLERIAN HORMONE AS PREDICTORS OF OVARIAN RESPONSE IN INTRACYTOPLASMIC SPERM INJECTION (ICSI) PATIENTS: A COMPARATIVE ANALYSIS
Author
Dr. Vanusha
Email
keyword
Antral follicle count (AFC), Anti-mullerian hormone (AMH), Ovarian response, Intracytoplasmic sperm injection (ICSI), Ovarian stimulation.
Abstract
This study aimed to assess whether antral follicle count (AFC) and antimullerian hormone (AMH) levels serve as reliable predictors of ovarian response in women undergoing intracytoplasmic sperm injection (ICSI). The study cohort comprised 112 participants aged between 25 and 42 years. Serum levels of estradiol (E2), luteinizing hormone (LH), folliclestimulating hormone (FSH), and AMH were measured via a serum test. Additionally, antral follicle count was determined on day 3 of the menstrual cycle, with antral follicles sized between 2 and 6 mm being considered. Ovarian stimulation was carried out using a long protocol, followed by induction of ovulation with human chorionic gonadotropin (hCG) once at least three follicles reached a diameter of 17 mm. Oocyte retrieval was performed under ultrasound guidance 36 hours posthCG administration. Poor ovarian response was defined as inadequate follicular growth resulting in less than 4 oocytes retrieved, while normal response was characterized by the retrieval of four or more oocytes. Statistical analysis was conducted using SPSS 16.0 software, with participants categorized into two groups based on ovarian response. The normal responder group exhibited an average of 12.27 ± 6.06 oocytes retrieved, whereas the poor responder group yielded 2.22 ± 1.24 oocytes. Multiple regression analysis revealed that both AMH and AFC significantly predicted ovarian response, with AFC demonstrating a prediction value of 1.528 ± 1.175. Notably, AFC was found to be a superior predictor of ovarian response compared to AMH levels. AMH and AFC are good predictors of ovarian response; AFC is better.
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