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American Journal of Oral Medicine and Radiology

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
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Abstract
Title
COMPARATIVE ANALYSIS OF TRAMADOL AND LORNOXICAM FOR POST-OPERATIVE PAIN RELIEF IN ENT SURGICAL PROCEDURES: A RANDOMIZED CONTROLLED TRIAL
Author
Dr Payal Bhattacharya, Dr P Prashanth Kumar
Email
keyword
Ear, Nose, Throat, Tramadol, Lornoxicam, Pain Relief
Abstract
This prospective, randomized, double-blind controlled trial aimed to assess the analgesic efficacy of tramadol compared to lornoxicam in postoperative pain management for patients undergoing ear, nose, and throat (ENT) surgical procedures. Two hundred and forty ASA class I-II patients, who had undergone elective ENT surgery under general anesthesia, were randomly allocated to three groups. Group L received 8 mg lornoxicam IV, Group T received 1 mg/kg tramadol IV, and Group C received IV saline after anesthesia induction pre-surgery. Postoperative pain, evaluated using the visual analogue scale (VAS), demonstrated significantly higher scores in Group C compared to Groups L and T at 30 minutes, and 1, 2, 4, and 6 hours postoperatively, with no significant difference between Groups L and T. Surgeon-assessed intraoperative blood loss did not differ significantly among the three groups. The most common adverse events in all groups were nausea and vomiting, with a significantly higher incidence in the placebo group than in the other two groups. Tramadol 1 mg/kg exhibited comparable efficacy to lornoxicam 8 mg in providing postoperative pain relief for ENT surgery patients. Both medications reduced the need for postoperative opioids, thereby minimizing associated adverse effects
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