Acta Biomedica Scientia

INCIDENCE AND CHARACTERISTICS, PATHOLOGICAL CONDITION OF BULLOUS PEMPHIGOID IN PEDIATRIC GROUP

Sajja Prakash1, Harikumar ReddyA

drpebyreddy@gmail.com

Direct Immunofluorescence, Cicatricial Pemphigoid, Epidermolysis Bullosa

Bullous problems are a complicated organization of disorders which remain an enigma and a project the clinical profession in trendy and the dermatologists and pediatricians specially. Pediatric cutaneous bullous disorders involve extra consideration due to the fact the connection between epidermis and dermis isn't well residential, pores and skin is thinner with better permeability of stratum corneum and absence of first hand history in newborn and infants. The present study aims to incidence and characteristics, pathological condition of Bullous pemphigoid in pediatric group. The study group comprises children in age group between 0 and 14 years, presenting with intact blisters attending the Skin and VD outpatient Department, Sri lakshmi Narayana Institute Of Medical Sciences and SreeBalaji Medical college and Hospital . All cases were evaluated by means of standard proforma which included a detailed history, thorough clinical examination with appropriate investigations where ever required. Majority of the cases were in the age range of 5–10 years (63% or 19 cases) followed by 11–14 years (20% or 6 cases), 2–6 years (10% or 3 cases), and 0–2 years (7% or 2 cases), respectively. The mean age of the study population was 9.36± 3.62 years (mean ± SD). A positive family history was associated with all the subtypes of EB. Rest of the diseases had proven no circle of relatives history of similar diseases. Total 17 (57%) were male and 13 (43%) were female. Male: female ratio was 1.3:2, which reflected an overall male prevalence.DIF became no longer an alternative to histopathology however complementary to the latter. A right correlation between clinical, histopathological, and DIF findings is vital for the very last analysis of VB problems