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Acta Biomedica Scientia

Volume 4, Issue 3, 2017
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
ADA LEVELS IN BRONCHOALVEOLAR LAVAGE FLUID AS DIAGNOSTIC INDICATORS FOR PULMONARY TUBERCULOSIS: A COMPREHENSIVE STUDY
Author
Dr. V. Naga Basava Raju
Email
raju.vnb@gmail.com
keyword
Pulmonary tuberculosis, ADA, BAL Bronchoalveolar lavage
Abstract
Currently, tuberculosis (TB) diagnostic tests take a long time. In this study, ADA in bronchoalveolar lavage fluid was evaluated for its diagnostic utility in treating pulmonary TB. AFB was not found in sputum smears of patients with suspected pulmonary TB. A comparison was made between study groups regarding ADA levels in BAL fluids. We included 126 patients, 30 of whom had pulmonary tuberculosis, 66 of whom had other pulmonary diseases, and 30 healthy subjects as a control. According to BAL fluid samples, there was mean levels of ADA of 3.13 ± 1.55, 1.42 ± 1.05, and 1.82 ± 0.79, respectively. As compared to the other two groups, pulmonary TB had a significantly higher infection rate (P 0.001). In ROC curves, 3.5 IU/L was selected as a cut off value were most sensitive (57%) and specific (84%) for diagnosing TB. However, a negative result from the BAL fluid from TB patients shows higher ADA activity than BAL fluid from other diseases, but that test cannot exclude TB
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