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Acta Biomedica Scientia

Volume 1, Issue 2, 2013
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
ANTIPYRETIC ACTIVITY OF METHANOL EXTRACT OF GRACILARIA DURA (AG.) J.AG. (RED SEAWEED) IN HARE ISLAND, THOOTHUKUDI, TAMIL NADU, INDIA
Author
John Peter Paul J*1 and Shri Devi SDK2
Email
johnarock2008@yahoo.com
keyword
Red seaweed, Gracilaria dura, Methanol extract, Antipyretic activity, Pyrexia.
Abstract
The present study was aimed to investigate the antipyretic activity of the methanol extract of Gracilaria dura (Ag.) J.Ag. collected from Hare island, Thoothukudi, Tamil Nadu, India on albino mice. Paracetamol (10mg/kg) was used as standard drug. The antipyretic activity of Gracilaria dura (Ag.) J.Ag. was determined by Brewer’s yeast induced pyrexia on albino mice. The various methanol extract doses used were 200mg/kg and 400mg/kg body weight of mice. 400mg/kg methanol extract of Gracilaria dura (Ag.) J.Ag. showed significant decrease in body temperature while 200mg/kg methanol extract showed less effect. 400mg/kg methanol extract exhibited closely significant (p<0.05) decrease in elevated body temperature as compared to standard drug. From the study it was concluded that the methanol crude extract of Gracilaria dura (Ag.) J.Ag. can be used for antipyretic activity.
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