Acta Biomedica Scientia

CLINICAL AND SEROLOGICAL CHARACTERISTICS OF NAIL PSORIASIS IN PATIENTS: FINDINGS FROM A CROSSSECTIONAL STUDY

Dr Akansh Jain

akanshjain001@gmail.com

Psoriasis, Peptide antibodies, Psoriatic arthritis

A lifetime incidence of 80-90% of people with psoriasis are affected by nail involvement. As well as predicting joint disease, it may indicate the severity of cutaneous involvement. In spite of this, the therapy has been little studied and evaluated, particularly among Indian psoriatic patients. This study assessed nail involvement and quality of life impairment in psoriasis patients as well as nail involvement clinical profile. Our study focused on nail psoriasis patients with consecutive cutaneous (psoriasis area severity index score) and nail psoriasis. Nail disease was assessed using a quality of life score of 10. Inflammatory markers, anticyclic citrullinated peptide antibodies, and joint disease were assessed in all patients. The concomitant psoriatic arthritis was found in 12 of our 45 patients with nail psoriasis. In the survey, the average severity index was 16.2 ± 7.5. In the survey, ninety-two percent of respondents reported pitting, 89.9% onycholysis, and 84.8% subungual hyperkeratosis. The mean nail psoriasis severity index score was 81.5 ± 30.7 and mean nail psoriasis quality of life 10 was 2.2 ± 0.6. In 26/45 patients (59.2%), the erythrocyte sedimentation rate was raised and the CRP levels were elevated; rheumatoid factor was positive in 7/45 (17.1%) and anticyclic citrullinated peptide antibodies were raised in 5/45 (12.7%). Researchers have found that nail involvement does not correlate well with the extent of cutaneous disease in Indian patients with nail psoriasis. Additionally, nail disease has little effect on patients' quality of life. The quality of life should be measured using an Indian-specific questionnaire. Patients with concomitant arthritis had higher serum markers than those without