American Journal of Oral Medicine and Radiology

STUDIES ON WHETHER CENTRAL VENOUS CATHETERS ARE BENEFICIAL DURING ELECTIVE BRAIN SURGERY

Nagaraju M 1*, Veluru Srinivasulu2

Nagaraju@gmail.com

OSMF- Oral submucous fibrosis, I.P.- Indian pharmaceutical, IU- International unit, W/V- Weight/ volume.

Clinical outcomes after elective supratentorial intracranial surgeries may be improved by using central venous catheters (CVC). A two-arm, single-center retrospective study compared elective intracranial surgeries carried out with and without CVCs. Standard procedures for anesthesia were modified, ultimately eliminating the requirement for CVCs for supratentorial surgery. The primary outcome was the number of peri-operative adverse events (AEs). Researchers studied the data of 621 patients (301 who had a CVC and 320 who did not). There were similarities in the patient profiles of both study groups. During the study, 132 adverse events were reported (81 in the CVC group compared to 51 in the control group) that involved neurological, neurosurgical, cardiovascular, and mortality concerns. Patients with CVC have nearly twice the number of AEs as those without (OR adjusted = 1.98; 95 percent confidence interval [1.28-3.06]; p 0.002). In 1.0 percent of the cases, complications such as pneumothorax and arterial malpuncture occurred. Treatment time in the ICU for CVC patients was 22 (19;24) hours, compared to 21 (19;24) hours (p = 0.413). There was also no difference between the groups' length of hospital stay (9 (7;13) vs. 8 (7;11) days, p = 0.210). A considerable difference was found between the CVC and normal groups in the number of minutes needed for ventilation (350 (300; 440) vs. 335 (281;405) minutes, and induction time (40 (35;50) vs 30 (25;35) minutes, p = 0.001. There was no difference in inflammation markers or antibiotic therapy postoperatively. Retrospective analysis of our data shows that patients with CVCs have no significant advantages over patients without any CVCs during elective neurosurgical procedures.