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American Journal of Oral Medicine and Radiology

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
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Abstract
Title
MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS BY TWO DIFFERENT REGIMENS
Author
Shubahshree M1. Nath, Anilgovind Rao Ghom2, Savita Ghom2, Ajit Mishra2, Arpan Aash1, Akhil Dwivedi
Email
drshubhashreem@gmail.com
keyword
OSMF- Oral submucous fibrosis, I.P.- Indian pharmaceutical, IU- International unit, W/V- Weight/ volume
Abstract
Oral submucous fibrosis is a precancerous condition of the oral mucosa. It also causes chronic inflammation and progressive fibrosis. Here in this study, we had taken 20 patients and randomly divided them into two groups, Group A treated with Calendula officinalis extract gel 2mg twice daily for 12 weeks and Group B treated with Triamcinolone acetonide(10mg/ml) + Hyaluronidase (1500 IU) at 1-week interval for 3 months. Treatment modalities depends upon two criteria’s: Burning sensation and Mouth opening. An unpaired t-test was used to compare the pre and post-treatment burning sensation and mouth opening. P<0.001 is highly significant. Triamcinolone acetonide shows a significant result in the reduction of mouth opening followed by Calendula officinalis. Calendula officinalis topical application may need longevity to attain the result. As per our knowledge, none of the studies have been done on Calendula officinalis for mouth-opening improvement in oral submucous fibrosis. In our study, it was observed that Calendula officinalis was found to be the best non-invasive, safe and cost-effective therapy for mouth opening in Grade II OSMF patients. In burning sensation, Calendula officinalis shows 100% results in the reduction of burning sensation compared to Triamcinolone acetonide shows 70% approx. Patients need not be worried about recurrent visits, they can use it by themselves (Calendula officinalis extract gel). In the current clinical evidence, Calendula officinalis shows a significant result in the management of oral submucous fibrosis, further study on Calendula officinalis may enlighten the facts to speak for themselves
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