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American Journal of Oral Medicine and Radiology

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Oral Medicine and Radiology
Issn
XXX-XXXX (Print), 2394 - 7721 (Online)
Frequency
bi-annual
Email
editorajomr@mcmed.us
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Abstract
Title
A POLYMORPHISM IN HAPTOGLOBIN MAY AFFECT THE LEVEL OF RISKS ASSOCIATED WITH CARDIOVASCULAR DISEASE BIOMARKERS IN PREVIOUSLY HYPERTENSIVE PREGNANT WOMEN
Author
Dr. Bhavya G
Email
Bhavya@gmail.com
keyword
words
Abstract
Cardiovascular disease risk is increased when someone suffers from preeclampsia (PE). Inflammatory, anti-oxidant, and angiogenic properties of HP genotype may modulate the risk of PE through Peripheral tissues and hepatocytes, which synthesize HP as a result of oxidative stress. Among 352 women age 2-16, we conducted a prospective study old, of whom 165 had experienced PE in the past. As part of our study, we examined demographic, anthropometric, and hemodynamic markers including as well as liver function tests (AST and ALT), lipid profiles (total LDL cholesterol, HDL cholesterol, nonHDL cholesterol, and apolipoprotein A and B), we also evaluate C-reactive protein (CRP), myeloperoxidase (MPO), nitric oxide metabolites (total and nitrites), and CRP (C-reactive protein) levels. Additionally, we investigate the relationship between All these biomarkers are associated with Hp genetic polymorphisms and their influence on PE and the prognosis of its remote cardiovascular disease. Hp 1/2 variants may modulate the variation of biomarkers associated with preeclamptic events (MPO, nitrites, and ALT), which was observed previously in hypertensive and normotensive women with preeclampsia. Women premenopausal with a Heart disease may be more prevalent in people with PE history when combined with these biomarkers
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