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European journal of molecular biology and biochemistry

Volume 11, Issue 1, 2024
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Purchase
Abstract
Title
POLYVALENT CROTALIDAE IMMUNE FAB IN CHILDREN: ACUTE HYPERSENSITIVITY REACTIONS
Author
Dr.Lal Bahadur Sastri, Dr.Siva kumar
Email
Sastri@gmail.com
keyword
Hypersensitivity reaction, Pediatric, Antivenom, Crotalid
Abstract
Acute hypersensitivity responses in children who receive Crotalidae Polyvalent Immune Fab (CPIF) have been studied. problematic due to Because of their diminutive stature and large age spans, and varied classifications. This is a chart study of Crotalid neurotoxic venom patients aged 13 and under who were treated with CPIF among November 2016 and November 2018. The primary outcome was the appearance approximately 3 hours of the CPIF infusion began, you experience any of the symptoms listed: urticaria, wheezing, or breathing problems discomfort, anaphylaxis, hypertension, nausea, and/or vomit. Demographic , CPIF dosage for control and multiple doses, bite location, degree of care, and length of stay were all investigated. all taken into consideration. all obtained. In the end, CPIF was used to treat 34 patients. The children varied in age from ten months to 13 years. With a range from one to eleven days, the average duration of stay is two days. The average duration of stay was two days, and twenty-one patients (60 percent) were male. Twenty-four patients (70.6 percent) were brought to the ICU.CPIF caused no acute hypersensitivity reactions in any of the subjects. This group did not have any acute hypersensitivity responses to CPIF. With the usage of CPIF in paediatric patients, such responses are uncommon
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