Abstract
Title
A HISTORICAL COHORT INVESTIGATION OF PERIOPERATIVE RISK VARIABLES IN INDIVIDUALS WITH IDIOPATHIC PULMONARY FIBROSIS
Author
Dr. Reddy Varaprasad babu D
Email
Reddy@gmail.com
keyword
Preoperative , pulmonary fibrosis, patients
Abstract
The overall mortality rate for Idiopathic Pulmonary Fibrosis is increasing, with a 28.4 percent rise in males and 41.3 percent
increase in females when corrected for age. The research does not provide a full picture of perioperative outcomes in
patients with Idiopathic Pulmonary Fibrosis. In Idiopathic Pulmonary Fibrosis patients who had diagnostic bronchoalveolar
lavage, there was an elevated risk of acute aggravation of Idiopathic Pulmonary Fibrosis. Furthermore, surgical lung biopsy
for the diagnosis of Idiopathic Pulmonary Fibrosis has been linked to a 2.1 percent incidence of Acute exacerbation -
Idiopathic Pulmonary Fibrosis and a 5.1-7.1 percent 30-day death rate. In addition, lung cancer patients with Idiopathic
Pulmonary Fibrosis have a greater rate of resection-related morbidity and mortality than those without Idiopathic Pulmonary
Fibrosis. To evaluate the perioperative risk variables in individuals with idiopathic pulmonary fibrosis. One-year mortality
was associated with increasing age (RR, 1.50; 95 percent confidence interval, 1.27 to 1.79; P<0.001), former tobacco
smoking status (RR, 2.44; 95 percent confidence interval, 1.32 to 4.52; P<0.004), preoperative oral steroid use (RR, 2.17; 95
percent confidence interval, 1.34 to 3.51; P<0.002), and absence of intraoperative dexamethasone administration (RR, 0.19;
95) This is the first study to demonstrate a link between preoperative home oxygen consumption and postoperative acute
respiratory worsening in Idiopathic Pulmonary Fibrosis patients. In addition, in our group, a longer operation length was
related with an increased risk of acute respiratory worsening. Because of our discovery that preoperative home oxygen
consumption is a predictor of postoperative acute respiratory worsening, we believe that this variable is the most clinically
relevant and useful for the perioperative risk stratification of Idiopathic Pulmonary Fibrosis patients. In patients with fibrotic
Interstitial lung disease, admission with acute respiratory worsening has been related with higher in-hospital and postdischarge mortality, regardless of the underlying Interstitial lung disease aetiology Furthermore, in patients undergoing
thoracic surgery, increased intraoperative fluid administration has been linked to a higher risk of postoperative acute
exacerbation of IP. We discovered a significant relationship between higher surgical duration and increased acute
respiratory worsening. Patients with Idiopathic Pulmonary Fibrosis had a high link between their preoperative home oxygen
need and their postoperative acute respiratory worsening, which was demonstrated in a study. Patients with this type of
medical history may benefit from higher postoperative risk stratification, which may be indicated by home oxygen use and an anticipated longer surgical procedure