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Acta Biomedica Scientia

Volume 4, Issue 3, 2017
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
PROSPECTIVE STUDY OF C-REACTIVE PROTEIN LEVELS IN DIAGNOSIS OF ACUTE APPENDICITIS IN SOUTH INDIANS
Author
1 Kalyan Seetharamaiah V, 2Manoj Kumar Yatagiri, 3Narendra
Email
drvrvkk@gmail.com
keyword
C-reactive protein, Appendix, Appendectomy, White cell count, Acute abdomen
Abstract
Acute appendicitis is one of the most common surgical emergencies. Approximately 7.0% of the population will have appendicitis in their lifetime with the peak incidence occurring between the age of 10 and 30 years. The classical history of peri umbilical pain at beginning and later shifting to right iliac fossa is present in only 50% cases. Clinical assessment outweighs the use of investigations in the diagnosis of acute appendicitis. Nevertheless, white cell count (WCC) and C-reactive protein (CRP) are regularly measured in patients with suspected appendicitis. C-reactive protein (CRP) is used routinely in many hospitals to evaluate patients with an acute abdomen. C-reactive protein is an acute phase reactant synthesized by liver in response to tissue injury. Serial measurement of CRP can improve the accuracy of diagnosing acute appendicitis. Data The source of data was from pretested proforma which takes into account clinical history, general physical examination, relevant investigations, imaging modalities. They were included after explaining them about the study and taking their written consent. In our study CRP test sensitivity was 92.00%, specificity was 84.00 %, positive predictive value was 96.00%, negative predictive value was 66.00% and diagnostic accuracy was 92.00%
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