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American Journal of Biological and Pharmaceutical Research

Volume 11, Issue 1, 2024
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
ANTI-CANDIDAL ACTIVITIES OFSepia aculeateINK EXTRACT AGAINST MULTIPLE RESISTANT Candida albicans CAUSING ORAL CANDIDIASIS
Author
P.Bharthi1,P.Mani2*, M.Ramasamy3
Email
master.maniji@gmail.com
keyword
Sepia aculeate ink, Ethanol fraction, Antimicrobial and Zone of inhibition
Abstract
This study was carried out to evaluate the anti microbial activity of water, ethanol, methanol, acetone, hexane and butanol crude extract and fractions of Sepia aculeate ink. The antimicrobial activity was determined by the disc diffusion method and significant inhibitory concentrationagainst fungal strain. The combining ethanol with methanol at 2:18 concentration moderately inhibits (6 mm inhibition zone) Candida albicans than all individual extract and fractions. In the GC-MS analysis 65 bioactive phytochemical compounds were identified in the ethanolic fraction of Sepia aculeate ink.. The results indicated that fractions of Sepia aculeate ink were highly potent as anticandidal agent.
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