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European journal of molecular biology and biochemistry

Volume 11, Issue 1, 2024
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
RELATIONSHIP BETWEEN HOMOCYSTEINE LEVEL AND RISK OF DIABETIC MELLITUS WITH AND WITHOUT CHRONIC KIDNEY DISEASE
Author
Sai Ravi Kiran Biri1, SLV Sankeerthi CH2, Seema Darotiya3, Prabhakar Reddy E4*
Email
drpebyreddy@gmail.com
keyword
Homocysteine, Chronic kidney disease, hyperhomocysteinemia
Abstract
Chronic Kidney Disease (CKD) is famous to cause hyperhomocysteinemia which contributes to extended cardiovascular morbidity and mortalities. Thus, present study has a look at aimed to determine the homocysteine stage in patients with chronic kidney disease. Seventy patients with CKD have been recruited within this examined, and their fasting plasma homocysteine levels was measured. Normal plasma homocysteine level became considered to be below 15 ?mol/litre. Out of 70 patients with CKD (Males: 57, Females:13 mean age 35-60), 52 patients had stage 5 CKD. Hyperhomocysteinemia turned into discovered in 74.2% of CKD patients. 25.7% had moderate hyperhomocysteinemia. End-level renal diseases patients had extended occurrence of hyperhomocysteinemia. There is no massive difference in hyperhomocysteinemia levels between patients undergoing dialysis and without dialysis. Hyperhomocysteinemia is a particularly prevalent condition seen in CKD patients.
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