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Acta Biomedica Scientia

Volume 6, Issue 3, 2019
Mcmed International
Acta Biomedica Scientia
Issn
2348 - 215X (Print), 2348 - 2168 (Online)
Frequency
bi-annual
Email
editorabs@mcmed.us
Journal Home page
http://mcmed.us/journal/abs
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Abstract
Title
COMPARISON OF SERUM VITAMIN D LEVELS IN PATIENTS WITH VITILIGO AND CONTROLS
Author
K. Narayanan, S. Raja
Email
drpebyreddy@gmail.com
keyword
Vitiligo, Vitamin D, Autoimmune Diseases, Etiopathogenesis
Abstract
Vitiligo, an autoimmune disorder caused by the destruction of melanocytes in the skin, is characterized by depigmented macules of different shapes. Vitiligo is an acquired depigmentary disorder having social and psychological aspects. Current research data suggest that complex interplay between genetic, autoimmune aberrations and oxidative stress are the key pathways mediating the destruction of melanocytes in vitiligo. To study the clinico-epidemiological profile of vitiligo patients and to detect serum vitamin D levels and determinewhether patients with vitiligo have lower serum vitamin D levels compared to controls. Significantly lower vitamin D levels were found in majority of vitiligo patients,vitamin D levels and the type of vitiligo in patients. However, owing to the widespread levels of vitamin D deficiency in our country, further studies involving a larger sample size are required.Based on the results obtained in the present study, we can conclude that vitamin D deficiency is present in vitiligo patients, suggesting that vitamin D deficiency may play a role in the pathogenesis of vitiligo
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