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European journal of molecular biology and biochemistry

Volume 6, Issue 1, 2019
Mcmed International
European journal of molecular biology and biochemistry
Issn
2348 - 2192 (Print), 2348 - 2206 (Online)
Frequency
bi-annual
Email
editorejmbb@mcmed.us
Journal Home page
http://mcmed.us/journal/ejmbb
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Abstract
Title
INFLAMMATORY MARKERS IN CRITICALLY ILL PATIENTS WITH VENOUS THROMBOSIS – A TERTIARY HOSPITAL-BASED STUDY
Author
Dr. Shaheen B Shaikh, Dr. Ismail H M, Dr. Bhavya R, Dr. Ganesh P, Sarfaraz Shaikh5
Email
drshaheenshaikh@yenepoya.edu.in
keyword
Deep Vein Thrombosis, Pulmonary embolism, Serum Homocysteine levels.
Abstract
Objectives -Vein Thrombosis represents a major public health problem, exacting a significant human and economic toll on the Nation. Venous thrombosis is an important and possibly preventable cause of morbidity and mortality in hospitalized patients. The objective of this study was to analyze the inflammatory markers in venous thrombosis. Materials and Methods- A cross-sectional study was conducted on patients admitted to tertiary Hospitals. The study was conducted on 59 radiographically confirmed cases of venous thrombosis. Informed written consent was obtained for participation in the study and conduction of investigations. The study was conducted between the period of November 2017 and September 2019. Results- The mean age of the study group was 43.6 years (SD= ±16.4) ranging from 20 to 72years. Out of the 59 patients, 48 were males (81.4%) and 11 were female (18.6%). The mean Body mass index of the patients was 24.33 ± 2.84 kg/m2. Among 59 patients, 48 patients ( 81.3%)had elevated CRP. 46 patients (77%) had elevated Serum Homocysteine levels(>15?mol/L). Among 59 participants 74.6 % had low HDL, 61% had High LDL, 45% had high Triglycerides. Total Cholesterol was elevated by 40.7 %. D dimer levels were elevated in 98. 3 %. Conclusion- We conclude that unprovoked venous thrombosis is a common problem among patients 20-29 yrs, male gender, BMI> 25 kg/m2 presenting to tertiary care hospital. Inflammatory markers were significantly elevated in venous thrombosis
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