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American Journal of Biological and Pharmaceutical Research

Volume 7, Issue 2, 2020
Mcmed International
American Journal of Biological and Pharmaceutical Research
Issn
2348 - 2176 (Print), 2348 - 2184 (Online)
Frequency
bi-annual
Email
editorajbpr@mcmed.us
Journal Home page
http://mcmed.us/journal/ajbpr
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Abstract
Title
DEVELOPMENT OF POLYHERBAL FORMULATIONS TO TREAT COLORECTAL CANCER
Author
Srikanth Choudary Pallothu*, M.Purushothaman, Madhusudhan Malladi, Kathiravan P, Sravanthi Chirra
Email
srikanthpallothu@gmail.com
keyword
Anticancer capsules, Piper, Clove, in vitro.
Abstract
Surgery (removing the cancer in an operation) is the most common treatment for all stages of colon cancer, Cryosurgery, Radiation therapy, Chemotherapy. As a part of chemotherapy, lots of anticancer drugs are in the market, but the main problem associated with these drugs is their side effects. Because of chemotherapy treatment side effects, the patient needs secondary palliative care treatment. Plant medicines are well known for their non-toxic side effects, so the objective of the study is to develop a drug from medicinal plant against colon cancer with non-toxic side effects. It plays an important role in the discovery of lead compound for development of conventional drugs. About 60% of currently used anticancer agents are derived from natural source (i.e. plants). Phytochemically the plant has been investigated for cardenolides, alkaloids, triterpenes and saponins and it is found to contain a variety of triterpenes and steroidal compounds and also to find out, a newer synthetic drug, for its anti-colon cancer potential and its toxic profile. In the present study, different formulations were prepared using herbs and the same were used to study the anticancer potential of the extract and to synthesize new anticancer formulation
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